Mercury is a ubiquitous environmental toxin that causes a wide range of adv
erse health effects in humans. Three forms of mercury (elemental, inorganic
, and organic) exist, and each has its own profile of toxicity. Exposure to
mercury typically occurs by inhalation or ingestion. Readily absorbed afte
r its inhalation, mercury can be an indoor air pollutant, for example, afte
r spills of elemental mercury in the home; however, industry emissions with
resulting ambient air pollution remain the most important source of inhale
d mercury. Because fresh-water and ocean fish may contain large amounts of
mercury, children and pregnant women can have significant exposure if they
consume excessive amounts of fish. The developing fetus and young children
are thought to be disproportionately affected by mercury exposure, because
many aspects of development, particularly brain maturation, can be disturbe
d by the presence of mercury. Minimizing mercury exposure is, therefore, es
sential to optimal child health. This review provides pediatricians with cu
rrent information on mercury, including environmental sources, toxicity, an
d treatment and prevention of mercury exposure.