Experimental oral polio vaccines and acquired immune deficiency syndrome

Authors
Citation
E. Hooper, Experimental oral polio vaccines and acquired immune deficiency syndrome, PHI T ROY B, 356(1410), 2001, pp. 803-814
Citations number
31
Categorie Soggetti
Multidisciplinary,"Experimental Biology
Journal title
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY OF LONDON SERIES B-BIOLOGICAL SCIENCES
ISSN journal
09628436 → ACNP
Volume
356
Issue
1410
Year of publication
2001
Pages
803 - 814
Database
ISI
SICI code
0962-8436(20010629)356:1410<803:EOPVAA>2.0.ZU;2-2
Abstract
The simian immunodeficiency virus (SIV) of the common chimpanzee is widely acknowledged as the direct ancestor of HIV-1. There is increasing historica l evidence that during the late 1950s, kidneys were routinely excised from central African chimpanzees by scientists who were collaborating with the p olio vaccine research of Dr Hilary Koprowski, and sent-inter alia-to vaccin e-making laboratories in the USA and Africa, and to unspecified destination s in Belgium. While there is no direct evidence that cells from these kidne ys were used as a substrate for growing Dr Koprowski's oral polio vaccines, there is a startling coincidence between places in Africa where his CHAT v accine was fed, and the first appearances in the world of HIV-1 group M and group-m-related AIDS. Because of the enormous implications of the hypothes is that AIDS may be an unintended iatrogenic (physician-caused) disease, it is almost inevitable that this theory will engender heated opposition from many of those in the scientific establishment, and those with vested inter ests.