Citation
T. Xiang et al., Studies on the hepatocyte protective activity and the structure-activity relationships of quinic acid and caffeic acid derivatives from the flower buds of Lonicera bournei, PLANTA MED, 67(4), 2001, pp. 322-325
Citations number
20
Categorie Soggetti
Pharmacology & Toxicology
Journal title
PLANTA MEDICA
ISSN journal
00320943
→ ACNP
Volume
67
Issue
4
Year of publication
2001
Pages
322 - 325
Database
ISI
SICI code
0032-0943(200106)67:4<322:SOTHPA>2.0.ZU;2-U
Abstract
13 quinic acid derivatives along with caffeic acid, methyl caffeate, myo-in
ositol, bis[5-formylfurfuryl] ether and 6,7-dihydroxycoumarin were isolated
from the ethanol extract of the flower buds of Lonicero bournei Hemsl., am
ong which 8 compounds were firstly obtained from this genus. The effects of
different solvent soluble fractions of the ethanol extract and the pure co
mpounds on heptocyte death induced by D-galactosamine (D-GalN)ltumor necros
is factor alpha (TNF-alpha) were studied, and the structure-activity relati
onships were also discussed.