New antioxidant and antimicrobial ellagic acid derivatives from Pteleopsishylodendron

Bioassay-guided isolation of two new compounds, 3,4-methylenedioxy-3'-O-met hyl-4'-O-glucoside ellagic acid (1) and the pteleoellagic acid derivative ( 2), from the stem bark of Pteleopsis hylodendron is reported along with 3,4 -methylenedioxy-3'-O-methyl ellagic acid (3), 3,3'-di-O-methyl ellagic acid (4) and 3,3:4'-tri-O-methyl ellagic acid (5), which were obtained for the first time from this plant. The structures of these compounds were elucidat ed with the help of spectroscopic studies. Compounds 1 and 4 were found to have significant antioxidant activity, while compounds 1-4 showed antibacte rial activity against different pathogenic bacteria.