Separation of the water-soluble fraction of peanut skins led to the isolati
on of 8 flavonoids and two novel indole alkaloids. Two new flavonoid glycos
ides have been identified as isorhamnetin 3-O-[2-O-beta -glucopyranosyl-6-O
-alpha -rhamnopyrano-syl]-pi beta -glucopyranoside and 3'5,7-trihydroxyisof
lavone-4'-methoxy-3'-O-beta -glucopyranoside. Two alkaloids are 2-methoxyl-
3-(3-indolyl)-propionic acid and 2-hydroxyl-3-[3-(l -N-methyl)-indolyl]-pro
pionic acid. These isolated flavonoids were evaluated for their free radica
l scavenging activity and protein glycation inhibitory effects.