The effect of revascularisation of an ischaemic lower limb an leukotriene E4 production

Authors
Rossi, P Kuukasjarvi, P Salenius, JP Riutta, A
Citation
P. Rossi et al., The effect of revascularisation of an ischaemic lower limb an leukotriene E4 production, PROS LEUK E, 64(6), 2001, pp. 289-290
Citations number
15
Categorie Soggetti
Cell & Developmental Biology
Journal title
PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS
ISSN journal
09523278 → ACNP
Volume
64
Issue
6
Year of publication
2001
Pages
289 - 290
Database
ISI
SICI code
0952-3278(200106)64:6<289:TEOROA>2.0.ZU;2-4
Abstract
It has previously been shown that leukotriene E4 production is increased bo th in acute and chronic lower limb ischaemia. The aim of this study was to measure the effect of revascularisation on leuktriene E4 excretion in chron ic lower limb ischaemia. Revascularisation did not affect significantly on leukotriene E4 excretion (preop. 34.9 +/-7.1 pg/mg creatinine, postop. 24.5 +/-4.7 pg/mg creatinine, n=10, P < 0.238). We suggest that the enhanced le ukotriene E4 production continues after revascularisation which may have a therapeutical implication. (C) 2001 Harcourt Publishers Ltd.