Purpose: Development of a software for fully automated image analysis of la
teral lumbar spine X-rays. Material and method: Using the concept of active
shape models, we developed a software that produces a form model of the lu
mbar spine from lateral lumbar spine radiographs and runs an automated imag
e segmentation. This model is able to detect lumbar vertebrae automatically
after the filtering of digitized X-ray images. The model was trained with
20 lateral lumbar spine radiographs with no pathological findings before we
evaluated the software with 30 further X-ray images which were sorted by i
mage quality ranging from one (best) to three (worst). There were 10 images
for each quality. Results: image recognition strongly depended on image qu
ality. In group one 52 and in group two 51 out of 60 vertebral bodies inclu
ding the sacrum were recognized, but in group three only 18 vertebral bodie
s were properly identified. Conclusion: Fully automated and reliable recogn
ition of vertebral bodies from lateral spine radiographs using the concept
of active shape models is possible. The precision of this technique is limi
ted by the superposition of different structures. Further improvements are
necessary. Therefore standardized image quality and enlargement of the trai
ning data set are required.