Sc(BINOL)(2)Li: a new heterobimetallic catalyst for the asymmetric Strecker reaction

Authors
Chavarot, M Byrne, JJ Chavant, PY Vallee, Y
Citation
M. Chavarot et al., Sc(BINOL)(2)Li: a new heterobimetallic catalyst for the asymmetric Strecker reaction, TETRAHEDR-A, 12(8), 2001, pp. 1147-1150
Citations number
20
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON-ASYMMETRY
ISSN journal
09574166 → ACNP
Volume
12
Issue
8
Year of publication
2001
Pages
1147 - 1150
Database
ISI
SICI code
0957-4166(20010521)12:8<1147:SANHCF>2.0.ZU;2-Z
Abstract
The new chiral heterobimetallic complex Sc(BINOL)(2)Li 1 was prepared and u sed as a catalyst in the enantioselective addition of a cyanide source (HCN or TMSCN) to several imines. High conversion rates and enantiomeric e exce sses (e.e.s) as high as 95% were obtained. (C) 2001 Elsevier Science Ltd. A ll rights reserved.