Changes in biochemical markers of bone metabolism and BMD during the firstyear after a hip fracture

We measured the levels of biochemical markers of bone formation and bone re sorption in hip fracture patients preoperatively and after 6 and 12 months, Bone densitometry was done with quantitative computer tomography (QCT), du al-energy X-ray absorptiometry (DXA) and heel ultrasound. After 6 months, the biochemical markers of bone formation and bone resorpti on had increased. The levels remained high after 1 year and no change occur red between 6 and 12 months, We found no correlations between biochemical b one markers and bone density/ stiffness on admission and change in bone min eral density (BMD) during the first postoperative year, despite the changes in bone markers and bone density. In our opinion, biochemical bone markers can not be used to predict bone lo ss in the individual patient after a hip fracture.