La. Bastian et Jt. Piscitelli, IS THIS PATIENT PREGNANT - CAN YOU RELIABLY RULE IN OR RULE OUT EARLY-PREGNANCY BY CLINICAL EXAMINATION, JAMA, the journal of the American Medical Association, 278(7), 1997, pp. 586-591
This review addresses a common problem facing the clinician: ''When tr
eating or evaluating a woman of childbearing years, what is the value
of historical or physical examination features in determining the prob
ability of early pregnancy?'' We focus on the clinical examination fin
dings that may help the clinician rule in or rule out early pregnancy.
Generally accepted indicators of pregnancy include amenorrhea, mornin
g sickness, tender or tingling breasts, and, after 8 weeks' gestationa
l age, an enlarged uterus with a soft cervix. We reviewed the value ti
e, sensitivity and specificity) of these indicators, as well as home p
regnancy test results, as predictors of the diagnosis of early pregnan
cy. The available evidence suggests that some historical features, whe
n absent, are fair but not reliable for ruling out pregnancy. When dia
gnosing early pregnancy, the clinician should not rely on the clinical
examination or a home pregnancy test-a laboratory test should be requ
ested.