Pe. Slater, CHRONIC ARTHROPATHY AFTER RUBELLA VACCINATION IN WOMEN - FALSE ALARM, JAMA, the journal of the American Medical Association, 278(7), 1997, pp. 594-595
The last large epidemic of rubella in the United States was in 1964 wh
en almost half a million cases were reported. The National Communicabl
e Disease Center, now the Centers for Disease Control and Prevention,
estimated the true size of the 1964 epidemic as 12.5 million cases, an
d at least 20 000 clinically evident cases of the congenital rubella s
yndrome (CRS) were subsequently reported.(1) The first rubella vaccine
was licensed in the United States in 1969, and from that year on rube
lla and CRS incidence began to decline. In 1994, there were 227 report
ed cases of rubella and 7 cases of CRS2; in 1995, there were 128 cases
of rubella-the lowest number in history-and 6 cases of CRS3; and in 1
996, there were 210 cases of rubella (CRS data are not yet available).
(4) Through June 1997, only 64 cases of rubella had been reported in t
he United States.(5)