Comparison of effects of Ioxaglate versus Iomeprol on histamine and tryptase release in patients with ischemic cardiomyopathy

Authors
Rodriguez, RM Gueant, JL Aimone-Gastin, I Angioi, M Abdelmoutaleb, I Saint-Laudy, J Gerard, P Namour, F Grentzinger, A Romano, A Juillere, Y Danchin, N
Citation
Rm. Rodriguez et al., Comparison of effects of Ioxaglate versus Iomeprol on histamine and tryptase release in patients with ischemic cardiomyopathy, AM J CARD, 88(2), 2001, pp. 185
Citations number
19
Categorie Soggetti
Cardiovascular & Respiratory Systems","Cardiovascular & Hematology Research
Journal title
AMERICAN JOURNAL OF CARDIOLOGY
ISSN journal
00029149 → ACNP
Volume
88
Issue
2
Year of publication
2001
Database
ISI
SICI code
0002-9149(20010715)88:2<185:COEOIV>2.0.ZU;2-U
Abstract
We observed a release of histamine, but not of tryptase, in arterial blood from 64 patients with ischemic heart disease and 24 patients without corona ry disease, which was provoked by ioxaglate, a ionic compound, but was not provoked by iomeprol, a nonionic radiocontrast compound. The release of his tamine in arterial blood after ionic contrast medium injection was higher i n patients with ischemic heart disease compared with patients without coron ary disease, suggesting that an increased release from heart mast cells pre viously observed exists also for systemic blood basophils.