Autoimmune peripheral neuropathies with anti-MAG antibodies and hematological disorders. Five cases

Objective. - The aim of this study was to report our experience with autoim mune nenropathies associated with hematological disorders and to describe t heir etiological and clinical polymorphism. Patients and methods. - A retrospective study was conducted in five patient s with autoimmune peripheral neuropathies with anti-MAG (myelin-associated glycoprotein) antibodies. Results. - Autoimmune neuropathies were associated with Waldenstrom's macro globulinemia (n=2), Hodgkin disease (n=1), chronic lymphocytic leukemia (n= 1) and idiopathic polyclonal B lymphoproliferation (n=1), Most of the patie nts had a sensorial polyneuropathy, predominant in the legs, exhibiting slo w progress, Our patients showed a disappointing response to chemotherapy wi th stabilization or short response.