We report the case of a 50 year-old man factor VIII deficient haemophiliac
and hepatitis C cirrhosis. The patient underwent orthotopic liver transplan
tation because of episodes of variceal bleeding and encephalopathy. He rece
ived factor VIII replacement therapy perioperatively. Factor VIII returned
to normal within 24 hours postoperatively and factor VIII replacement was s
topped. Liver transplantation can be considered as definitive therapy for h
aemophilia. (C) 2001 Editions scientifiques et medicales Elsevier SAS.