HeartMate III: Pump design for a centrifugal LVAD with a magnetically levitated rotor

Authors
Bourque, K Gernes, DB Loree, HM Richardson, JS Poirier, VL Barletta, N Fleischli, A Foiera, G Gempp, TM Schoeb, R Litwak, KN Akimoto, T Watach, MJ Litwak, P
Citation
K. Bourque et al., HeartMate III: Pump design for a centrifugal LVAD with a magnetically levitated rotor, ASAIO J, 47(4), 2001, pp. 401-405
Citations number
9
Categorie Soggetti
Research/Laboratory Medicine & Medical Tecnology
Journal title
ASAIO JOURNAL
ISSN journal
10582916 → ACNP
Volume
47
Issue
4
Year of publication
2001
Pages
401 - 405
Database
ISI
SICI code
1058-2916(200107/08)47:4<401:HIPDFA>2.0.ZU;2-7
Abstract
A long-term, compact left ventricular assist device (LVAD), the HeartMate i ll, has been designed and fabricated, featuring a centrifugal pump with a m agnetically levitated rotor. The pump has been optimized by in vitro testin g to achieve a design point of 7 L/min against 135 mm Hg at high hydrodynam ic efficiency (30%) and to be capable of up to 10 L/min under such a load. Furthermore, the pump has demonstrated no mechanical failures, low hemolysi s (4-10 mg/dl plasma free Hb), and low thrombogenicity during six (40, 27, 59, 42, 27, and 49-day) in vivo bovine studies.