Spectral analysis of heart rate and arterial pressure variabilities is a po
werful noninvasive tool, which is increasingly used to infer alterations of
cardiovascular autonomic regulation in a variety of physiological and path
ophysiological conditions, such as hypertension, myocardial infarction and
congestive heart failure. A most important methodological issue to properly
interpret the results obtained by the spectral analysis of cardiovascular
variability signals is represented by the attribution of neurophysiological
correlates to these spectral components. In this regard, recent applicatio
ns of spectral techniques to the evaluation of the oscillatory properties o
f sympathetic efferent activity in animals, as well as in humans, offer a n
ew approach to a better understanding of the relationship between cardiovas
cular oscillations and autonomic regulation. (C) 2001 Elsevier Science B.V.
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