Mitochondrial cytopathies are a diverse group of inherited and acquired dis
orders that result in inadequate energy production. They can be caused by i
nheritable genetic mutations, acquired somatic mutations, exposure to toxin
s (including some prescription medications), and the aging process itself.
In addition, a number of well-described diseases can decrease mitochondrial
energy production; these include hyperthyroidism, hypothyroidism, and hype
rlipidemia.