Tandem radical addition reactions to substituted indoles under atom-transfer and oxidative conditions

Authors
Byers, JH Kosterlitz, JA Steinberg, PL
Citation
Jh. Byers et al., Tandem radical addition reactions to substituted indoles under atom-transfer and oxidative conditions, CR AC S IIC, 4(6), 2001, pp. 471-476
Citations number
19
Categorie Soggetti
Chemistry
Journal title
COMPTES RENDUS DE L ACADEMIE DES SCIENCES SERIE II FASCICULE C-CHIMIE
ISSN journal
13871609 → ACNP
Volume
4
Issue
6
Year of publication
2001
Pages
471 - 476
Database
ISI
SICI code
1387-1609(200106)4:6<471:TRARTS>2.0.ZU;2-S
Abstract
The dimethyl methylmalonyl radical was generated upon photolysis of dimethy l bromomethylmalonate or treatment of dimethyl methylmalonate with Mn(OAc)( 3).2 H2O. This radical was added to an exocyclic olefin appended to 1-acyl or 3-acyl indoles, with subsequent cyclization to generate 1,2 or 2,3- fuse d indole derivatives, respectively. (C) 2001 Academie des sciences / Editio ns scientifiques et medicales Elsevier SAS.