Genomic imprinting: Mother maintains methylation marks

Authors
Dean, W Ferguson-Smith, A
Citation
W. Dean et A. Ferguson-smith, Genomic imprinting: Mother maintains methylation marks, CURR BIOL, 11(13), 2001, pp. R527-R530
Citations number
23
Categorie Soggetti
Experimental Biology
Journal title
CURRENT BIOLOGY
ISSN journal
09609822 → ACNP
Volume
11
Issue
13
Year of publication
2001
Pages
R527 - R530
Database
ISI
SICI code
0960-9822(20010710)11:13<R527:GIMMMM>2.0.ZU;2-8
Abstract
A DNA methyltransferase has been identified that plays a role in maintainin g the methylation status of imprinted genes. Interestingly, although expres sed in the unfertilised egg, this enzyme functions only during one round of replication in the eight-cell embryo.