Human puromycin-sensitive aminopeptidase: cloning of 3 ' UTR, evidence fora polymorphism at aa 140 and refined chromosomal localization to 17q21

Authors
Bauer, WO Nanda, I Beck, G Schmid, M Jakob, F
Citation
Wo. Bauer et al., Human puromycin-sensitive aminopeptidase: cloning of 3 ' UTR, evidence fora polymorphism at aa 140 and refined chromosomal localization to 17q21, CYTOG C GEN, 92(3-4), 2001, pp. 221-224
Citations number
10
Categorie Soggetti
Molecular Biology & Genetics
Journal title
CYTOGENETICS AND CELL GENETICS
ISSN journal
03010171 → ACNP
Volume
92
Issue
3-4
Year of publication
2001
Pages
221 - 224
Database
ISI
SICI code
0301-0171(2001)92:3-4<221:HPACO3>2.0.ZU;2-Y
Abstract
Puromycin-sensitive aminopeptidase is a predominantly cytoplasmatic zinc-de pendent exopeptidase. Its physiological function is not known to date. Here we report data on tissue distribution, a polymorphism within the coding re gion and the complete 3' UTR. The gene (NPEPPS alias PSA) was physically ma pped to chromosome 17q21.2 --> q21.32 using fluorescence in situ hybridizat ion. Copyright (C) 2001 S. Karger AG, Basel.