Mb. Mortensen et al., Initial experience with new dedicated needles for laparoscopic ultrasound-guided fine-needle aspiration and histological biopsies, ENDOSCOPY, 33(7), 2001, pp. 585-589
Background and Study Aims: Laparoscopic ultrasonography (LUS) is an importa
nt imaging modality during laparoscopic staging of intra-abdominal malignan
cies, but LUS-assisted biopsy is often difficult or impossible. We report a
newly developed inbuilt biopsy system for direct LUS-guided fine-needle as
piration (FNA) and Tru-cut biopsies.
Patients and Methods: LUS-guided biopsy was performed in 20 patients with u
pper gastrointestinal tract tumors. The biopsied lesions had either not bee
n previously detected by other imaging modalities or had been inaccessible,
or the biopsy sample had been inadequate. Primary diagnosis, duration of b
iopsy procedure, needle monitoring (visibility, penetration, and deviation)
, complications, technical failures, and pathological findings were prospec
tively recorded.
Results: 44 biopsies were performed with 25 needles (19, 20, and 22-G), Nee
dle monitoring and penetration were good or acceptable in 18 patients (90%)
, Slight needle deviation (<10 mm) was seen in eight patients (40%), The LU
S-guided biopsy specimen was sufficient for analysis in 13 patients (65%),
In two additional patients, adequate material was obtained, but pathologica
l examination was impossible owing to incorrect handling of the specimen. T
he biopsy procedures lasted 16.3 minutes (range 10-20 minutes) and no compl
ications were seen.
Conclusions: LUS-guided fine-needle aspiration or Tru-cut biopsy is possibl
e using this newly developed biopsy system. These preliminary data suggest
that LUS-guided biopsy may further improve the diagnostic possibilities of
LUS.