Animal models for male pattern (androgenetic) alopecia

The stump-tailed macaque (Macaca arctoides) appears to be a suitable biolog ical model for human androgenetic alopecia. The expense, danger, and low av ailability compromise its value but macaques currently remain the model of choice. Rodent models, both testosterone induced alopecia and various xenog raft approaches, show promise for elucidating fundamental information on no rmal and abnormal hair growth as well as serving as models to develop new t herapies to treat hair loss.