AGGRESSIVE ANGIOMYXOMA OF THE INGUINAL REGION - REPORT OF ONE CASE INA MAN WITH GASTRIC-CANCER

Aggressive angiomyxoma is a distinctive and very rare soft tissue tumo r occurring almost exclusively in women. Only seven cases occurring in men have been previously reported. We herein report a case of a 74-ye ar-old man who was admitted to our hospital presenting with a huge rig ht inguinal mass that had grown over a 14-year period, in order to und ergo surgical treatment for gastric cancer. The inguinal tumor was wel l-defined and demonstrated a glistening appearance on the cut surface. Histologically, the tumor was composed of bland-looking spindle and s tellate cells with delicate cytoplasmic processes, which sparsely popu lated the fibromyxoid matrix. A prominent vascular component was also present. Immunohistochemically, the stromal cells stained consistently for vimentin and variably for muscle-specific actin, but not for alph a-smooth muscle actin, desmin, and S-100 protein. The gastric cancer w as microscopically diagnosed to be papillary adenocarcinoma with seros al invasion and showing immunoreactivity for p53 protein, but not for aggressive angiomyxoma.