Cj. Tai et al., Complete atrio-ventricular block as a major clinical presentation of the primary cardiac lymphoma: a case report, JPN J CLIN, 31(5), 2001, pp. 217-220
It is uncommon for malignant lymphomas to present primarily with cardiac in
vasion as the main clinical feature. What we are interested in is not only
where the disease is, but also those symptoms that it may induce. Sudden on
set of complete atrio-ventricular block is one of the most common clinical
presentations. Cardiac tamponade is another common disease entity which, if
it locates over outlets of great vessels, may also exert symptoms of obstr
uctive vessels. Diagnosis can be made by needle aspiration under the guidan
ce of transcutaneous or transesophageal echocardiography. Both CT scan and
MRI play positive roles in the diagnosis of cardiac lymphomas, and the latt
er can even provide much more image information than the former. We report
a 70-year-old male with primary cardiac lymphoma with initial clinical pict
ures of sudden onset of complete atrio-ventricular block. Chemotherapy was
utilized with cyclophosphamide, vincristine and prednisolone (COP) initiall
y for four courses and followed by adding doxorubicin (CHOP) for another th
ree courses. The patient was still in remission status after treatment for
2 years.