Effect of tracheal intubation or laryngeal mask Airway (TM) insertion on intraocular pressure using balanced anesthesia with sevoflurane and remifentanil

Study Objectives: To study the effect of tracheal intubation or laryngeal m ask airway (LMA) insertion an intraocular pressure (IOP) in strabismus pati ents undergoing balanced anesthesia with sevoflurane and remifentanil. Design: Open, prospective, randomized study. Setting: Tertiary care academic medical institution. Patients: 40 adult ASA physical status I and II patients scheduled for effe ctive strabismus surgery. Intervention: Patients were randomized to receive either tracheal intubation or LMA insertion following mask induction with sevoflurane in combination with IV remifentanil Measurements: Intraocular p ressure, mean arterial pressure (MAP); and heart rate (HR) were measured be fore induction, immediately following induction, and after airway insertion . Main Results: Intraocular pressure after tracheal intubation or LMA inser tion did not differ significantly from preoperative baseline values. Mean. arterial pressure and HR did not significantly differ between groups at any time point. Conclusions: Remifentanil and sevoflurane are not associated with an increa se in IOP response during tracheal intubation or LMA insertion above baseli ne in healthy patients undergoing ophthalmic surgery. (C) 2001 by Elsevier Science Inc.