Though diffusion-weighted MRI has been applied to various intracranial lesi
ons, few reports had been presented about cerebral hamartomatous lesions in
patients with neurofibromatosis type 1 (NF1). In this study, we report the
interval changes of apparent diffusion coefficient (ADC) in a presumed ham
artomatous lesion. In our case, the ADC increased slightly over a 3 year pe
riod. This diffusion property may provide specific insight into the etiolog
y of cerebral hamartomatous lesions observed in NF1.