Ej. Stelnicki et al., Early treatment of severe mandibular hypoplasia with distraction mesenchymogenesis and bilateral free fibula flaps, J CRANIOF S, 12(4), 2001, pp. 337-348
The technique of distraction has revolutionized the treatment of mandibular
hypoplasia; however, presently large mandibular defects still require bone
grafts. Microvascular grafting is commonly used in adults. Conversely, in
pediatric reconstruction, nonvascularized rib grafts remain standard. Unfor
tunately, resorption of nonvascularized bone remains a major issue, particu
larly when soft tissue is hypoplastic. This case study represents a combina
tion of techniques in the treatment of severe mandibular deficiency, and in
troduces the concept of distraction mesenchymogenesis. The patient was a 21
/2-year-old boy with severe bilateral Pruzansky class III mandibular hypopl
asia. He had a permanent open mouth posture, an overjet of 23 mm, and was u
nable to move the lower mandibular segment. His oropharyngeal airway diamet
er was 2.2 mm and he was tracheostomy dependent, The patient was treated wi
th distraction of the lower jaw mesenchyme followed by bilateral functional
free fibular microvascular flaps containing reinnervated muscle. This crea
ted a well-vascularized body, ramus, and condyle bilaterally within an adeq
uate soft-tissue envelope. Postoperatively, the overjet was reduced to 5 mm
. The patient can now actively move his mandible. Airway diameter increased
to 10 mm, and the patient is able to tolerate intermittent tracheostomy pl
ugging. This innovative combination of techniques allows early intervention
, limits,graft resorption, and improves airway control.