A new tripler STR system without irregular alleles by silver staining and its potential application to forensic analysis

Authors
Yoshimoto, T Yamamoto, T Uchihi, R Tamaki, K Huang, XL Mizutani, M Tanaka, M Armour, JAL Katsumata, Y
Citation
T. Yoshimoto et al., A new tripler STR system without irregular alleles by silver staining and its potential application to forensic analysis, J FOREN SCI, 46(3), 2001, pp. 448-452
Citations number
20
Categorie Soggetti
Research/Laboratory Medicine & Medical Tecnology
Journal title
JOURNAL OF FORENSIC SCIENCES
ISSN journal
00221198 → ACNP
Volume
46
Issue
3
Year of publication
2001
Pages
448 - 452
Database
ISI
SICI code
0022-1198(200105)46:3<448:ANTSSW>2.0.ZU;2-7
Abstract
In order to increase the discriminating power of DNA analysis in forensic s cience, we devised a new tripler STR system using three novel STR loci we p reviously reported, D14S299 (wg1c5), D15S233 (wg1d1), and 9q2h2. We designa ted this system a CDH tripler system. The CDH tripler system showed a high discriminating power, especially in Caucasians. This system is composed of three STR loci showing only regular tetranucleotide repeat alleles. We easi ly enlarged the databases mainly of Japanese, using this system, and compar ed them with those of Caucasian and Chinese. This CDH tripler system theref ore appears to be useful for forensic practice.