Effects of eradication therapy on gastric emptying in patients with Helicobacter pylori-positive duodenal ulcers

In this study 28 patients with Helicobacter pylori-positive duodenal ulcers were treated with a 7-day triple-therapy regimen (omeprazole, clarithromyc in, amoxycillin). Gastric emptying time was measured scintigraphically befo re and after therapy. Only 13 patients attended regularly for their endosco pic and scintigraphic follow-ups. Gastric emptying time was 57.6 +/- 16.5 m in in 28 patients before therapy, and 44.4 +/- 13.9 min after therapy (44.7 +/- 7.9 min in the control group). The present study demonstrated gastric emptying time to be longer in the ulcer patients compared with healthy cont rols and that, after eradication therapy, gastric emptying time became almo st normal in the ulcer patients.