Organic reactions in aqueous medium - Part-XI: Effect of sonication on thereaction of benzoylacetone with semicarbazide hydrochloride in the formation of 3-phenyl-5-methylpyrazole and 3-phenyl-5-methylpyrazole-1-carboxamide

Reaction of benzoylacetone with semicarbazide hydrochloride has been studie d An intensive investigation has been carried out under varying conditions. Since benzoylacetone is not soluble in water, it does not react with semic arbazide hydrochloride in aqueous medium under ordinary conditions. The rea ction has been induced to proceed under the effect of power ultrasound Ar a result methods for the synthesis of 3-phenyl-5-methylpyrazole-1-carboxamid e (I) in ethanol-water mixture and 3-phenyl-5-methylpyrazle (1) in water in very high yields have been developed.