Diastereocontrolled Strecker reaction using (S)-5-phenylmorpholin-2-one

Authors
Harwood, LM Drew, MGB Hughes, DJ Vickers, RJ
Citation
Lm. Harwood et al., Diastereocontrolled Strecker reaction using (S)-5-phenylmorpholin-2-one, J CHEM S P1, (14), 2001, pp. 1581-1583
Citations number
22
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1
ISSN journal
14727781 → ACNP
Issue
14
Year of publication
2001
Pages
1581 - 1583
Database
ISI
SICI code
1472-7781(2001):14<1581:DSRU(>2.0.ZU;2-0
Abstract
Iminium ions derived from (S)-5-phenylmorpholin-2-one 1 undergo diastereose lective Strecker reactions using copper(I) cyanide and anhydrous hydrochlor ic acid; the major adducts may be degraded to D-alpha -amino acids.