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Isogalactofagomine lactam. A neutral nanomolar galactosidase inhibitor
Authors
Sohoel, H
Liang, XF
Bols, M
Citation
H. Sohoel et al., Isogalactofagomine lactam. A neutral nanomolar galactosidase inhibitor, J CHEM S P1, (14), 2001, pp. 1584-1585
Citations number
13
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1
ISSN journal
14727781 →
ACNP
Issue
14
Year of publication
2001
Pages
1584 - 1585
Database
ISI
SICI code
1472-7781(2001):14<1584:ILANNG>2.0.ZU;2-W
Abstract
4-Deoxy-4-hydroxymethyl-L-ribono-1,5-lactam (9) was synthesised and found t o be a potent inhibitor of beta -galactosidase from Aspergillus oryzae with a K-i of 18 nM.