v-Triazolines. Part 42. Study on the reactivity of 4,5-dihydro-1-(6-methyl-2-oxo-2H-pyran-4-yl)-5-morpholino-v-triazoles. Synthetic approach to pyrano[4,3-b]pyrrol-4(1H)-ones

Authors
Erba, E Pocar, D Trimarco, P
Citation
E. Erba et al., v-Triazolines. Part 42. Study on the reactivity of 4,5-dihydro-1-(6-methyl-2-oxo-2H-pyran-4-yl)-5-morpholino-v-triazoles. Synthetic approach to pyrano[4,3-b]pyrrol-4(1H)-ones, J CHEM S P1, (14), 2001, pp. 1723-1728
Citations number
23
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1
ISSN journal
14727781 → ACNP
Issue
14
Year of publication
2001
Pages
1723 - 1728
Database
ISI
SICI code
1472-7781(2001):14<1723:VP4SOT>2.0.ZU;2-C
Abstract
Pyrolysis of 4-aryl-5-morpholino-4,5-dihydrotriazoles 3 affords two product s: pyrano[4,3-b]pyrrol-4(1H)-ones 4 and arylacetamidines 5. The reaction me chanism of this transformation is discussed and reaction conditions optimiz ed to enhance the formation of pyrrole-fused pyran-2-one derivatives 4. 2-A minoaziridines are considered to be key intermediates in this transformatio n.