Anaphylaxis after propofol infusion for Port-A-Cath insertion in a 35-yearold man

Anaphylaxis to propofol is rare and has not been previously reported in Asi a. We describe a 35-year-old man with nasopharyngeal carcinoma who develope d acute respiratory distress and hypotension after propofol infusion for pa renteral anesthesia for Port-A-Cath insertion. Chest roentgenogram showed b ilateral diffuse alveolar infiltrates. Respiratory failure ensued, and voca l cord swelling was found during endotracheal intubation. Hemodynamic data included a low cardiac index, a low systemic vascular resistance, and a hig h pulmonary vascular resistance. His condition and the shadows on the chest roentgenogram improved quickly after fluid challenge and the use of vasopr essors, antihistamine, and intravenous steroids. Early awareness and approp riate management are necessary to prevent a fatal outcome in patients with propofol anaphylaxis.