Md. Eckhardt et al., Prevalence and bothersomeness of lower urinary tract symptoms in benign prostatic hyperplasia and their impact on well-being, J UROL, 166(2), 2001, pp. 563-568
Purpose: We established the prevalence and bothersomeness of symptoms and t
heir impact on well-being in a large group of strictly selected men with lo
wer urinary tract symptoms suggestive of benign prostatic hyperplasia (BPH)
.
Materials and Methods: Included in our study were 475 consecutive men who m
et the criteria of the International Consensus Committee on BPH and voided
more than 150 mi. during uroflowmetry. International Prostate Symptom Score
s and quality of life score were determined. We included the 7 bothersomene
ss questions of the Symptom Problem Index and the 4 of the BPH Impact Index
of the American Urological Association Measurement Committee. These questi
ons refer to the degree of bothersomeness caused by urinary problems and ho
w they affect various health domains.
Results: The symptoms with the highest prevalence based on mean scores were
weak urinary stream, frequency and urgency. Urgency, nocturia and hesitanc
y were the most bothersome symptoms. Patients were only discouraged from pe
rforming normal daily activity when the symptom index exceeded 20. Incomple
te emptying and frequency bothersomeness correlated strongly, and weak urin
ary stream and hesitancy bothersomeness correlated weakly with all health a
nd quality of life domains.
Conclusions: Weak urinary stream, frequency and urgency were the most preva
lent symptoms, while urgency, nocturia and hesitancy were the most botherso
me symptoms. In contrast to weak urinary stream and hesitancy, the botherso
meness of incomplete emptying and frequency was strongly associated with we
ll-being.