Effect of residual stress on femoral arterial stress-strain behavior

It is well established that arteries are subjected to residual stress. Due to the effect of residual stress, the arteries open to a horse-shoe shape w hen a longitudinal cut is made on an excised arterial segment. Previously, the residual stress has been quantified by the opening angle of the horse-s hoe shape. We have employed a finite element analysis of the open arterial segment to restore the same to the original cylindrical shape and computed the circumferential strain as well as the stress distribution in the wall. In this study, the stress and strain distribution in the femoral arteries o f miniswine was computed with and without the residual stress for a range o f transmural pressures. Our analysis show ed that the residual stress has t he effect of redistribution of the circumferential stresses between the int ima and the adventitia under physiological loading. The redistribution of t he stress with the inclusion of residual stress may be important in the stu dies on effect of wall stresses on the endothelial and vascular smooth musc le cells.