In vitro activity of sertaconazole, fluconazole, ketoconazole, fenticonazole, clotrimazole and itraconazole against pathogenic vaginal yeast isolates

Authors
Palacin, C Tarrago, C Agut, J Guglietta, A
Citation
C. Palacin et al., In vitro activity of sertaconazole, fluconazole, ketoconazole, fenticonazole, clotrimazole and itraconazole against pathogenic vaginal yeast isolates, METH FIND E, 23(2), 2001, pp. 61-64
Citations number
21
Categorie Soggetti
Pharmacology & Toxicology
Journal title
METHODS AND FINDINGS IN EXPERIMENTAL AND CLINICAL PHARMACOLOGY
ISSN journal
03790355 → ACNP
Volume
23
Issue
2
Year of publication
2001
Pages
61 - 64
Database
ISI
SICI code
0379-0355(200103)23:2<61:IVAOSF>2.0.ZU;2-M
Abstract
The in vitro of sertaconazole was compared with those of the most commonly used vaginal antimycotic agents - fluconazole, ketoconazole, fenticonazole, clotrimazole and itraconazole - against 94 strains of clinical isolates of Candida spp. using a macrodilution method in Casitone C. parapsilosis, 1 f or C. krusei and 2 for C. tropicalis. These values show that sertaconazole is one of the most active products against yeasts causing vulvovaginal cand idiasis, its activity against C. glabrata being particularly relevant. (C) Prous Science. All rights reserved.