Minor antigen solves major problem

Authors
Dazzi, F Simpson, E Goldman, JM
Citation
F. Dazzi et al., Minor antigen solves major problem, NAT MED, 7(7), 2001, pp. 771-772
Citations number
11
Categorie Soggetti
Research/Laboratory Medicine & Medical Tecnology","Medical Research General Topics
Journal title
NATURE MEDICINE
ISSN journal
10788956 → ACNP
Volume
7
Issue
7
Year of publication
2001
Pages
771 - 772
Database
ISI
SICI code
1078-8956(200107)7:7<771:MASMP>2.0.ZU;2-O
Abstract
A mouse model for donor lymphocyte infusion reveals that a single immunodom inant minor H antigen is responsible for the beneficial effects of donor T lymphocytes against host leukemia. Separating the good from the bad could m ean the end of graft-versus-host disease in bone marrow transplants.