Fg. Davis et al., Prevalence estimates for primary brain tumors in the United States by behavior and major histology groups, NEURO-ONCOL, 3(3), 2001, pp. 152-158
Prevalence rates are used to supplement descriptions of disease and are una
vailable for all primary brain tumors in the United States. Data from two p
opulation-based tumor registries were obtained from the Central Brain Tumor
Registry of the United States and used to compute age-specific incidence r
ates (1985-1994) and survival curves for further use in a statistical model
to estimate prevalence rates. Prevalence rates were then used to estimate
the number of individuals living with a brain tumor diagnosis in the U,S, p
opulation for the year 2000, The overall incidence rate in these regions is
13.8 per 100,000 with 2-, 5-, and 10-year survival rates of 58%, 49%, and
38%, respectively. The prevalence rate for all primary brain tumors is 130.
8 per 100,000 with approximately 350,000 individuals estimated to be living
with this diagnosis in the United States in 2000, The prevalence rate for
malignant tumors, 29.5 per 100,000, is similar to previous reports. The pre
valence rate for benign tumors, 97.5 per 100,000, is new. Unlike incidence
data, the proportion land expected number) of existing benign tumors (75%,
267,000) is considerably greater than that for malignant tumors (23%, 81,00
0), reflecting the better prognosis of benign tumors diagnosed in individua
ls younger than 60 years old. These data underscore the impact of primary b
rain tumors in the U,S, health care system and emphasize the need for quali
ty-of-life considerations, particularly for those long-term survivors of be
nign tumors.