The subjects were 25 children including West syndrome, Lennox-Gastaut syndr
ome, childhood absence epilepsy (CAE) and localization-related epilepsies.
Clinical seizures occurred only during waking state in 14 patients (includi
ng the cases of West syndrome, CAE and epilepsy with myoclonic absences (EM
A)), only during sleeping state (especially during non-REM sleep in five pa
tients, including the case of benign epilepsy with centrotemporal spike), a
nd diffusely during waking and sleeping states in six patients (including t
he case of early infantile epileptic encephalopathy with suppression burst)
. These three types were observed in the cases of Lennox-Gastaut syndrome a
nd localization-related epilepsies. Subclinical ictal discharges occurred d
uring REM sleep in West syndrome, and during REM and non-REM sleep especial
ly during non-REM sleep in CAE and EMA.