Anaphylactic shock after injection of intradermal vaccine BCG

The authors describe the case of a 16-year-old male without any medical his tory who developed anaphylactic shock a few minutes after the injection of the intradermal vaccine EGG Pasteur. Chronology of events, lack of any othe r drug intake and the dramatic increase of serum tryptase level account for the anaphylactic reaction consecutive to vaccine injection. A few weeks af ter the accident, the allergic data don't reveal much. At this time, serum anti dextran IgG are significantly high (8 mg/L), suggesting the involvemen t of dextran in this severe adverse reaction. (C) 2001 Editions scientifiqu es et medicales Elsevier SAS.