Multicentric reference values for some quantities measured with Tina-Quant((R)) reagents systems and RD/Hitachi analysers

Ten clinical laboratories in different regions of Spain have shared the sea rch for reference individuals and the production of reference values for qu antities concerning ferritin, transferrin, rheumatoid factors. C-reactive p rotein and antistreptolysin O, using Tina-Quant((R)) reagents systems and R D/Hitachi analysers. All the logistic work has been done in co-operation wi th the supplier of the reagents and analysers (Roche Diagnostics Espana, S. L., Barcelona). The reference limits produced in the virtual laboratory are derived from the blend of reference values obtained by each laboratory. Th e multicentric reference limits were estimated according to the recommendat ions of the International Federation of Clinical Chemistry. The work done i s a model of co-operation between the in vitro diagnostic industry and clin ical laboratories for the production of reference values.