A purely synthetic, diversity amenable version of norephedrine thiols for the highly enantioselective diethylzinc addition to aldehydes

Authors
Jimeno, C Moyano, A Pericas, MA Riera, A
Citation
C. Jimeno et al., A purely synthetic, diversity amenable version of norephedrine thiols for the highly enantioselective diethylzinc addition to aldehydes, SYNLETT, (7), 2001, pp. 1155-1157
Citations number
29
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
SYNLETT
ISSN journal
09365214 → ACNP
Issue
7
Year of publication
2001
Pages
1155 - 1157
Database
ISI
SICI code
0936-5214(200107):7<1155:APSDAV>2.0.ZU;2-Y
Abstract
A new beta -aminothiol arising from purely synthetic yet enantiopure aminoa lcohols has bern prepared and successfully used in the addition of diethylz inc to aromatic aldehydes, yielding secondary alcohols in ee's up to 99%.