Plant cell-to-cell communication is achieved by membranous conduits called
plasmodesmata. which bridge the cytoplasm of neighboring cells. A growing b
ody of immunolocalization data shows an association of the cytoskeleton mac
hinery with plasmodesmata, The role of the cytoskeleton in the plasmodesmat
a-mediated transport has been well documented for virus movement, Because v
iruses are known to exploit existing host pathways and because the cytoskel
eton is involved in intracellular trafficking, the cytoskeleton is thought
to drive and target macromolecules to plasmodesmata. It is this link betwee
n plasmodesmata and the cytoskeleton that will be described here.