Aim: Schistosomiasis (Bilharzia, Bilharziasis) is one of the most prevalent
tropical diseases, with an increasing number of cases being imported into
Europe. Sonography is among the most valuable diagnostic tools for schistos
omiasis-related organ lesions. This review outlines typical findings and th
eir pathophysiological context. Method and Results: Bilharziasis of the uri
nary tract, usually due to Schistosoma (S.) haematobium, leads to diffuse o
r localized wall thickening of the bladder and the distal ureter with typic
al sonographic features. Upper urinary tract obstruction and rarely - bladd
er carcinoma may complicate the course and can also be detected sonographic
ally. The other species (S. mansoni, S. japonicum, S. mekongi, S. intercala
tum) primarily cause (entero-) colitis; the Value of sonography in this con
dition is yet undefined. In later stages, fibrotic liver involvement with p
ortal hypertension may develop (hepatosplenic schistosomiasis), leading to
typical ultrasound features which are nearly pathognomonic under endemic co
nditions: severe periportal echogenicity with S. mansoni, and a peculiar,,n
etwork pattern" of echogenic septa with S. japonicum. Sonographic indicator
s of portal hypertension may be identified and graded. Conclusion: In endem
ic areas in the tropics, sonography with simple portable machines offers a
unique opportunity to investigate morbidity on the community level non-inva
sively in large field surveys; it has thus become an important tool of clin
ical and epidemiological research.