Although given routinely as prophylaxis against wild-type measles to HIV-in
fected children, the live attenuated measles component of the MMR triple va
ccine also possesses potential for disease. We document a case of measles p
roven to be caused by vaccine strain in a HIV-infected child here in the UK
and discuss the clinical and immunological aspects. We also consider the n
ew guidelines for MMR vaccination in HIV-infected children adopted last yea
r in the USA. (C) 2001 Elsevier Science Ltd. All rights reserved.