The effects of psychiatric pharmacy services on clinical outcomes of acute
care psychiatric inpatients were studied. Patients recruited at a state psy
chiatric facility during phase 1 (October 1996-March 1997) served as the co
ntrol group and received only traditional centralized pharmaceutical servic
es and physician-requested psychiatric pharmacotherapy consultations.
Patients recruited during phase 2 (May-December 1997) received intensive ps
ychiatric pharmacy services and served as the experimental group. Pharmaceu
tical services during phase 2 included attending treatment team meetings, p
erforming baseline assessments and weekly reviews, providing pharmacotherap
y recommendations, obtaining medication histories, reviewing drug administr
ation records daily, monitoring for adverse drug reactions, conducting medi
cation education classes, and counseling patients before discharge. Outcome
Variables included clinical response determined with objective rating scal
es, cost of care, length of stay, adverse events, rate of acceptance of rec
ommendations, patient compliance with the first clinic visit scheduled afte
r discharge, quality of life, and patient satisfaction.
Data were analyzed for 48 patients in the control group and 45 patients in
the experimental group. There were no significant differences between the t
wo groups with respect to age, sex, duration of illness, number of hospital
izations, and number of months since the last hospitalization. Patients in
the experimental group showed significant improvements in clinical response
acid drug-induced extrapyramidal symptoms compared with the controls and w
ere highly satisfied with the pharmaceutical services they received. Medica
tion costs did not differ significantly, and length of stay was about 29 da
ys for each group.
The provision of clinical pharmacy services provided to inpatients in an ac
ute care psychiatric facility was associated with improvements in rating-sc
ale scores for clinical response and for drug-induced extrapyramidal sympto
ms.