TOOTH ERUPTION THROUGH AUTOGENOUS AND XENOGENOUS BONE TRANSPLANTS - AHISTOLOGICAL AND RADIOGRAPHIC EVALUATION IN BEAGLE DOGS

The effect of implanting autogenous and xenogenous (Bio-Oss) bone tran splants into metabolically active sites within beagle dog mandibles du ring permanent premolar tooth eruption was examined. Ten 14-week-old b eagles were used. Before commencing the radiographic experiments, meta l bone markers were placed in the caudal margin of the mandible at the age of 10 weeks. The deciduous first and third molar teeth were extra cted and their sockets over the permanent second and fourth premolars were implanted with autogenous particulate enchondral iliac crest bone , autogenous particulate membraneous mandibular body bone, xenogenous bovine anorganic bone mineral spongiosa granules (1-2 mm(3)) (Bio-Oss, Geistlich Pharma, Switzerland) or left empty. The third premolar serv ed as a control site. Standardized oblique lateral radiographs were ta ken once a week. A number of coordinates of defined points and structu res were determined by means of a coordinate digitizing system. Animal s were killed 4, 10 and 16 weeks after bone transplantation for histol ogical examination of the transplantation sites. All premolars showed no delay in eruption or disruption of crown and root development. On h istology, the Bio-Oss particles were not resorbed or integrated in the alveolar bone but were pushed forward into the gingiva. We have demon strated that there is no difference in the eruption curve of the perma nent premolars in the four groups (ANOVA P > 0.5) and that bone transp lantation has no inhibitory effect on eruption (ANOVA P > 0.3) and cro wn development of the underlying permanent premolar but that Bio-Oss d oes not have the same resorbable or integrating capability as autogeno us bone grafts.