MOTOR-ACTIVITY AND DAILY VARIATION OF SYMPTOM INTENSITY IN DEPRESSED-PATIENTS

Spontaneous motor activity measured by actigraphy and subjectively exp erienced intensity of symptoms were investigated in 16 unipolar depres sed inpatients with melancholic features. Patients felt significantly less active, awake, and more depressed in the morning compared to the evening. However, morning activity levels appeared significantly highe r compared to evening levels. Diurnal variations of symptoms were refl ected by actigraphically measured motor activity, which was negatively correlated with subjectively experienced symptom intensity. Increased motor activity may represent an observable, psychobiological, behavio ral equivalent of self-experienced depressive symptoms in major depres sion with melancholic features.