S. Kumar et al., Syntheses of curcumin bioconjugates and study of their antibacterial activities against beta-lactamase-producing microorganisms, BIOCONJ CHE, 12(4), 2001, pp. 464-469
In the present study cucumin bioconjugates, viz. di-O-glycinoylcurcumin (I)
, di-O-glycinoyl-C-4-glycylcurcumin (II), 5'-deoxy-5'-curcuminylthymidine (
5'-cur-T) (IV), and 2'-deoxy-2'-curcuminyluridine (2'-cur-U) (V) have been
synthesized and characterized by elemental analysis and H-1 NMR. The turmer
ic peptide (Tp) was isolated from the aqueous turmeric extract of the turme
ric rhizome. The antibacterial activity of these four bioconjugates and als
o of the turmeric peptide and sodium salt of curcumin (III) have been teste
d particularly for beta -lactamase-producing microorganisms.